What are the effects on the fetus of maternal Rh sensitization?... | Filo
What are the effects on the fetus of maternal Rh sensitization?... | Filo
5.8K viewsApr 14, 2025
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🌟👉 RH INCOMPATIBILITY - Rh incompatibility occurs when an Rh-negative mother carries an Rh-positive fetus. The mother’s immune system recognizes fetal Rh-positive red blood cells as foreign and forms anti-Rh (anti-D) antibodies. These antibodies cross the placenta in subsequent pregnancies and attack fetal red blood cells, leading to Hemolytic Disease of the Fetus and Newborn (HDFN) 🔬 HOW IT HAPPENS? (Pathophysiology) First pregnancy with Rh-positive fetus → sensitization occurs (fetomaternal
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🌟👉 RH INCOMPATIBILITY - Rh incompatibility occurs when an Rh-negative mother carries an Rh-positive fetus. The mother’s immune system recognizes fetal Rh-positive red blood cells as foreign and forms anti-Rh (anti-D) antibodies. These antibodies cross the placenta in subsequent pregnancies and attack fetal red blood cells, leading to Hemolytic Disease of the Fetus and Newborn (HDFN) 🔬 HOW IT HAPPENS? (Pathophysiology) First pregnancy with Rh-positive fetus → sensitization occurs (fetomaternal
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How much fetal blood is enough to cause sensitisation in mother which can lead to antibody response from mother to baby? Rh sensitization in an Rh-negative individual typically occurs when there is a mixing of Rh-positive fetal blood with the maternal circulation. As little as 0.1 mL of Rh-positive fetal blood can potentially cause sensitization in an Rh-negative mother. However, this risk can increase with larger quantities of fetal blood exposure. It is important for Rh-negative pregnant indiv
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Continued from previous video 📌Examples of events that can expose a woman to sensitization Sensitisation happens when a woman with rhesus negative blood (A-,B-, AB-, O-) is exposed to rhesus positive blood (A , B , AB , O ) usually during a previous pregnancy with an RhD positive baby. And her immune system produces antibodies to attack the positive blood cells of subsequent/ next pregnancies (Watch previous video) Sensitization events 👇 📌Abortion, miscarriages > 12 weeks pregnancy 📌Trauma t
Jan 8, 2025
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