Both Tabrizi and Yang think that knocking down MSH3 could stave off HD pathology. Tabrizi noted that MSH3 also modifies other run-on repeats, including those causing fragile X syndrome, myotonic ...

“This is a wonderful piece of work,” said Henrik Zetterberg at the University of Gothenburg, Sweden. He was not involved in ...

Unlike other prior studies that detected changes in AD markers following COVID-19 infection ( Jan 2021 news; May 2023 ...

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This variant is one of 31 intronic variants in SORL1 that compose a haplotype associated with a reduced risk of Alzheimer’s disease and with certain AD-related endophenotypes in people of East Asian ...

When it comes to tau tangles, cortical deposits receive the lion’s share of scientists’ attention, but it is the tiny subcortical regions where tangles originate that might set the course for ...