Primary objective To evaluate histopathological renal response in re-biopsy after induction therapy and to correlate with the Target Renal Response (TRR) and secondary objective: to correlate serum ...

Objectives To assess indirect costs (IDC) due to lost productivity in paid/unpaid labour, stratified by sex, in a national prospective observational multicentre Canadian SLE cohort. Methods Patients ...

Objective Cardiovascular diseases are a leading cause of morbidity and mortality in SLE. In this target population, ...

Objective Macrophages and kidney cell pyroptosis/ferroptosis could play an important role in the pathogenesis of lupus ...

Objective To investigate the relationship between adverse childhood experiences (ACEs) and health outcomes in childhood-onset ...

Lupus nephritis (LN) is one of the most serious complications of SLE, manifesting as haematuria and/or proteinuria, hypertension and ultimately kidney failure. Despite advances in immunomodulatory ...

Objective The multinational ERYTHRO (NCT06046534) study investigated the experience of patients with moderate-to-severe SLE initiating anifrolumab treatment through routine clinical practice as part ...

Objective Although current treatment recommendations for systemic lupus erythematosus (SLE) provide the option for biologic agents without prior failure of immunosuppressants (IS), data on this ...

Objectives To characterise the clinical presentation, laboratory findings, treatment approaches, and outcomes of systemic lupus erythematosus (SLE)-associated macrophage activation syndrome (MAS), and ...

Infectious agents especially viruses e.g. Epstein Barr virus contribute to systemic lupus erythematosus (SLE) pathogenesis and can trigger lupus disease activity by driving autoimmunity through ...