1 Department of Upper Gastro-intestinal Surgery, Hope Hospital, Salford Royal Hospitals NHS Trust, Manchester, UK 2 Department of Pathology, Hope Hospital, Salford Royal Hospitals NHS Trust, ...

Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK Dr A Walther, Molecular and Population Genetics, London Research Institute, Cancer Research UK, 44 Lincoln’s Inn Fields, London ...

Background Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency with evolving demographics and ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, ...

The GI tract is colonised by trillions of bacteria in a complex community collectively referred to as the gut microbiota. This metabolically active ‘foreign’ body contributes to host metabolism and ...

Background Ulcerative colitis (UC) is a chronic inflammatory condition of the intestinal tract that affects the rectum and colon. Ferroptosis is a type of cell death that is triggered by an excess of ...

Introduction Malnutrition results in prolonged inpatient stay, high readmission rates and poor clinical outcome. 1–3 Malnutrition in cirrhosis is a poor prognostic factor. 4 Assessing nutritional ...

Objective To evaluate mid-term outcomes and predictors of survival in non-operated patients with pancreatic intraductal papillary mucinous neoplasms (IPMNs) with worrisome features or high-risk ...

Introduction Training procedural skills in GI endoscopy once focused on threshold numbers. As threshold numbers poorly reflect individual competence, the focus gradually shifts towards a more ...

Objective Patients infected with Helicobacter pylori develop chronic gastritis with a subgroup progressing to further complications. The role of microbiota from the oral cavity swallowed with saliva ...

International consensus meetings in Padova and Vienna have attempted to rationalise the grading and classification of gastrointestinal epithelial neoplasia (GEN). With its minor adjustments, the ...

The treatment of IBD has evolved significantly over the past 15 years. Historically, steroids and immunosuppressive drugs, such as methotrexate (MTX), azathioprine (AZA) and 6-mercaptopurine (6-MP) ...