The Philadelphia Phillies host the Seattle Mariners in the final matchup of this three-game series at Citizens Bank Park. MLB odds list Philadelphia as a -140 favorite, while the total sits at 8.5. My Mariners vs. Phillies predictions expect a low-scoring affair this afternoon. Read on for my MLB picks for Wednesday, August 20.

Philadelphia Phillies ace Zack Wheeler had surgery Monday to remove a blood clot in his upper right arm, and the team says a timeline for his recovery remains uncertain.

When manager Rob Thomson walked to the mound to pull Cristopher Sánchez with one out in the seventh inning, fans began to stand and cheer. The starter handed Thomson the baseball, headed toward the dugout,

The Seattle Mariners' rough road trip experienced another bump in a 6-4 loss against the Philadelphia Phillies on Tuesday at Citizens Bank Park.

Pregame analysis and predictions of the Seattle Mariners vs. Philadelphia Phillies MLB game to be played on August 20, 2025 on ESPN.