Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment ...

Anti-N-methyl-D-aspartate (NMDA) encephalitis is marked by rapidly evolving and severe neuropsychiatric symptoms that can affect any age. This case illustrates a woman in her early 40s who was ...

A research team at Leipzig University has identified a mechanism in adhesion G protein-coupled receptors (adhesion GPCRs), a ...

For decades, the scientific theory of depression focused on chemicals — serotonin, norepinephrine and dopamine. Nearly every ...

A newly identified gene mutation may help explain why schizophrenia patients struggle to update their understanding of reality. The mutation disrupts a brain circuit involved in flexible ...

Immune checkpoint inhibitors have reshaped cancer treatment over the past decade, but the same immune activation that shrinks tumors can also turn against healthy tissue, including the brain. A ...

Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated. If cancer arises from cellular mutation, why don't ...

A new study published in Science Advances describes a potential target for therapies aimed at treating anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, also known as ‘Brain on Fire,’ an ...

BUFFALO, N.Y. – Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders.

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. The previous evidence for NMDARs containing N1, N2, and N3 ...