The University of Texas MD Anderson Cancer Center today announced a $10 million gift from Peggy and Carl Sewell to establish the Center for Cellular ...

Proxygen’s second lead candidate, CDK12, is a brain-penetrant glue degrader program designed to inactivate the transcriptional kinase CDK12, a target implicated in aggressive HER2-driven cancers and ...

(TP53), widely known as the “guardian of the genome,” is one of the most frequently altered genes in human cancer. While its canonical tumor-suppressive ...

ATP-binding cassette, subfamily C, member 8 and related genes are associated with pulmonary arterial hypertension.

Metabolic syndrome is a major global health concern, encompassing interconnected conditions such as obesity, hypertension, dyslipidemia, and insulin resistance. These metabolic disturbances ...

This manuscript has convincing data that provides a high-resolution structure of the Egl-RNA complex. The findings are important to understand the formation, stability, and interactions of this ...

Artificial intelligence is rapidly becoming the backbone of modern genomics, from pinpointing genetic variants to integrating multi-omics data for precision medicine. By enhancing accuracy, ...

Scientists have uncovered an unexpected way cells can generate cancer-driving proteins—by cutting RNA into shorter, functional fragments rather than following the standard blueprint. This process, ...

Understanding how drug discovery screening cascades are constructed and optimized is essential for minimizing false positives ...

A series of new genomic studies are transforming understanding of human adaptation over the past 10,000 years. Analyses of tens of thousands of ancient and modern genomes have uncovered hundreds of ...