Multiple system atrophy (MSA) is an adult-onset, rapidly progressive neurodegenerative disorder characterised by the aggregation of α-synuclein in oligodendroglial cytoplasmatic inclusions.1 ...

The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in ...

STING" molecular switch drives Alzheimer's brain inflammation. Blocking this switch protects synapses in new study.

Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”, or the “Company”), a clinical-stage biotechnology company leading the discovery and development of the next generation of allosteric small molecule ...

ATH434 reduced functional decline vs placebo at Week 52 on MuSyCA, a newly described MSA composite scale -- Effects seen on both daily function ...

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the accumulation of misfolded ...

New research suggests that tubulin may help prevent the toxic protein clumps associated with Alzheimer’s and Parkinson’s ...

Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by dopaminergic neuronal loss in the substantia nigra and intracellular accumulation of misfolded ...

People with Parkinson’s disease have α-synuclein clumps in the brain, but these aggregates are not the only thing clogging them up. Constipation plagues many PD patients, often decades before motor ...

KNOXVILLE, Tenn.--(BUSINESS WIRE)--#EnigmaBioUSA--Enigma Biomedical USA (EB USA) today announced that The Michael J. Fox Foundation for Parkinson’s Research (MJFF), has awarded EB USA $2 million for ...

Scientists have uncovered a potential new mechanism whereby α-synuclein pathology spreads. Like black holes, large densities of α-synuclein pull in surrounding matter. Among the victims trapped in ...