Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...
A mathematical model suggests that existing HPA-targeting drugs failed in clinical trials for mood disorders because the ...
This review focuses on intergenerational and transgenerational epigenetic inheritance in different plants, animal species and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The exposome is the measure of all the ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Metabolic requirements of dividing hepatocytes ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Homologous recombination is a largely ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The DNA-damaging agent Gemcitabine (GEM) is a ...
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