However, Kittle's presence as a run blocker and as a pass-catching threat helped the 49ers unlock a run game that was averaging an NFL-worst 3.1 yards per carry entering Sunday's contest.

The San Francisco 49ers are spending their fifth week this season without starting quarterback Brock Purdy as he continues to nurse a toe injury that he re-aggravated against the Jacksonville Jaguars.

The 49ers are starting backup quarterback Mac Jones, who will be making his fifth appearance in seven games in place of Brock Purdy. The Niners are getting somewhat healthier with the return of star tight end George Kittle,