A new platform for studying mtDNA mutations implicated in human disease could help accelerate treatments for mitochondrial ...

Mitochondria don’t just generate energy—they also carefully organize their own DNA in a surprisingly elegant way. Scientists have discovered that a long-overlooked phenomenon called “mitochondrial ...

EPFL scientists have discovered that a simple shape change in mitochondria helps cells evenly distribute their mitochondrial DNA, solving a long-standing puzzle.

Mitochondrial dysfunction is seen in many cardiac disorders. Understanding mitochondrial quality control (MQC) can help ...

Mitochondrial diseases are a heterogeneous group of disorders with varying clinical features caused by impaired function of the mitochondrial respiratory chain. The underlying cause can be gene ...

One study reported 8 live births from 22 women with pathogenic mtDNA variants who underwent mitochondrial donation through pronuclear transfer. None had signs of mitochondrial disease and heteroplasmy ...

A mitochondrial enzyme, Ak4, strengthens immune defense by promoting mitochondrial DNA synthesis and enhancing macrophage ...

Provide each team with a copy of "The Hunt for mtDNA" student handout. Explain to students what mtDNA is, how it differs from nuclear DNA, and how it is inherited (see Activity Answer for more ...

The vast majority of our DNA—the chromosomes in the nucleus of each cell—is just what you’d expect: a mix of genetic material from both mother and father. But mitochondria are an exception. They ...

You are a forensic scientist recruited to help solve a long-standing "missing persons" case. Mitochondrial DNA, or mtDNA for short, is the key to your success. Take careful notes as your teacher ...