This weekend represents the last 2025 regular-season series between the Los Angeles Dodgers and San Diego Padres. Unfortunately, the rivalry has cooled due to the Dodgers’ dominance over the Padres in head-to-head competition.

The LA Dodgers (73-56) visit the San Diego Padres (73-56) Saturday for the second game of their 3-game series at Petco Park. First pitch is scheduled for 8:40 p.m. ET (MLB.TV Free Game of the Day). Let's analyze BetMGM Sportsbook's MLB odds around the Dodgers vs. Padres odds and make our expert MLB picks and predictions for the best bets.

On a night when their chances to do viable damage were few and far between, the Dodgers had an opportunity they couldn't afford to waste in the top of the eighth inning. Hard-throwing Padres righty Mason Miller was on the mound.