They will head out on the road to face off against the Arizona Cardinals at 4:05 p.m. ET at State Farm Stadium. The 49ers will be looking to extend their current five-game winning streak. Last Sunday, ...

Who will win the San Francisco 49ers vs the Arizona Cardinals NFL Week 3 game today? The Arizona Cardinals and San Francisco 49ers play on Sunday, Sept. 21, at the 49ers' Levi's Stadium in a game on ...

Brock Purdy's pass was tipped at the line and the Arizona Cardinals snatched the ball from the air to secure a much-needed victory in San Francisco. Seconds earlier, Chad Ryland kicked a 35-yard field ...

The San Francisco 49ers will likely have to wait at least one more game until All-Pro tight end George Kittle returns to the field. Last month, George Kittle was placed on the injured reserve after ...

The San Francisco 49ers are the top seed in the NFC After Week 5. Who would have thought? The Philadelphia Eagles entered Week 5 undefeated at 4-0 but lost to the Denver Broncos, and because of ...

The San Francisco 49ers on Monday opened the practice window for second-year safety Malik Mustapha. Mustapha was participating in the individual portion of Monday's bonus practice for the 49ers ...

Listen in as San Francisco 49ers LB Fred Warner was wired for sound during the team's Week 4 matchup against the Jacksonville Jaguars, powered by ‪Cisco. Listen in as San Francisco 49ers OL Colton ...

SANTA CLARA – One-score games are all Alfred Collins and his fellow 49ers rookies know about the NFL, five tense weeks into their careers. “I’m just happy we’re winning,” Collins said Tuesday. “We ...