Published in Cell Reports, the study reveals how the molecular organization of cytotoxic T cells underpins their function, ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

This review examines how CAR-T cell therapy is expanding beyond blood cancers into solid tumors, autoimmune diseases, chronic ...

Image Caption: Protein structure of mammalian SETD2. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific ...

A new EMBO Reports study suggests that obesity can leave a lasting epigenetic imprint on CD4 T cells, delaying the restoration of adaptive immune balance after weight loss. Using mouse models and ...

Macrophages, the immune system’s front-line scavenger cells, do more than simply digest dead cells. A new study published in Nature Communications shows they actively extract nuclear DNA from dying ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells ...