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Lindsay Ess, who lost both hands and feet to an infection five years ago and received two new hands in a ground-breaking transplant, will be profiled on ABC News’ “Nightline” at 11:35 p.m. tonight.

Listening to the news can feel like a journey. But 1A guides you beyond the headlines – and cuts through the noise. Let's get to the heart of the story, together – on 1A.