Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

A preclinical study has reported that simultaneous inhibition of cyclin-dependent kinases 2 and 4/6 produced durable tumour ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Sidewinder achieves highly accurate assembly of long DNA sequences from scratch, offering a new leap forward for programmable biology ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

As AI accelerates, leaders must fundamentally reimagine their digital operating model, harnessing AI as a catalyst to ...

By blending scientific accuracy with creative design, one builder hopes to make the history of DNA accessible, interactive, ...

A compound from ginger stops cancer cells from making fats and drains their energy, exposing a metabolic weakness in cancer cells.