MethylScan is a low-cost blood test that detects cancers and organ diseases by analyzing DNA methylation, improving early diagnosis, and identifying disease origin.

A machine learning model analyzing CpG-based DNA methylation accurately predicted the origin of many different cancer types ...

By analyzing CpG-based DNA methylation, the model achieved 87% accuracy when applied to 31 cases representing 17 different cancer types.

Researchers at the Johns Hopkins Kimmel Cancer Center have developed a novel liquid biopsy approach to identify early-stage cancers by measuring the random variation in DNA methylation patterns, ...

Prevalence of androgen receptor ligand-binding domain mutations (AR-LBDm) in circulating tumor DNA (ctDNA) versus tissue biopsies in participants (pts) with metastatic castration-resistant prostate ...

Investigators at the Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test ...

A new DNA methylation-based blood test can identify type 2 diabetes patients at the highest risk of heart attack or stroke years in advance, beating traditional risk scores and opening the door to ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Our bodies do not age at a uniform rate. The speed at which one organ ages can differ greatly from another due to a range of lifestyle, environmental and genetic factors. Conventional tests provide a ...

A graphic of a purple and magenta Cas9 protein, which is a somewhat round, but uneven, ball, bound to a yellow and orange ...