Leptin is a cell-signalling hormone vital in the regulation of appetite, food intake and body weight. Studies have shown that an absence of leptin in the body or leptin resistance can lead to ...

Infants breastfed on demand exhibit a variety of feeding patterns and self-regulate their nutrient intake, but factors influencing their gastric emptying (GE) are poorly understood. Despite research ...

We report here that the delivery of leptin to the hypothalamus through intracranial gene transfer results in the efficient normalization of body weights in obese mice, using doses of recombinant virus ...

Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, Yale School of Medicine researchers have found that the hormone also ...

In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and ...

Leptin is a hormone that is produced in adipocytes and exerts its effects on the brain and several other peripheral tissues. It plays a crucial role in regulating endocrine functions and controlling ...

Leptin reduces food intake in part by enhancing satiety responses to gastrointestinal signals produced in response to food consumption. Glucagon-like peptide 1 (GLP-1), secreted by the intestine when ...

A long run feels the worst until it feels the best. That's primarily thanks to the runner's high -- those euphoric feelings that strike halfway through an endurance workout. Now, researchers have ...

The adipocyte hormone leptin is important in regulating energy homeostasis. Since severe lipodystrophy is associated with leptin deficiency, insulin resistance, hypertriglyceridemia, and hepatic ...

How does the Arctic tern (a sea bird) fly more than 80,000 miles in its roundtrip North Pole-to-South Pole migration? How does the Emperor penguin incubate eggs for months during the Antarctic winter ...