The microscopic image shows a nerve cell and a magnified view of the investigated synapses. Calcium was released at these sites using a UV flash, which triggered the release of the neurotransmitter.

For the first time, researchers have confirmed that selectively pruning certain synapses in the brain can paradoxically ...

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...

Every thought, memory, and feeling we experience depends on trillions of tiny connection points in the brain called synapses.

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

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Family with sequence similarity 19 member A5 (FAM19A5) is a secretory protein highly expressed in the brain that regulates synapse dynamics through its interaction with leucine-rich repeat-containing ...