There was a clarifying moment late in Wednesday’s two-and-a-half-hour-long oral argument in United States v. Skrmetti, a history-making challenge to Tennessee’s ban on gender-affirming care for minors.

The ruling could set a precedent for several challenges to state laws regarding sports participation, bathroom use and health care for adults.

The highest court in the United States is set to decide whether a statewide ban in Tennessee on gender-affirming medical care for minors is unconstitutional. The landmark case could have major consequences for transgender people across the country.