T lymphocytes, key mediators of the adaptive immune response, are activated when their T-cell receptors (TCRs) interact with cognate antigenic peptides displayed by major histocompatibility complex ...
The potential for personalized cancer treatment is fueling the need to identify T cell responses against neoantigens and other cancer-specific epitopes for the success of immunotherapy. Continuous ...
MHC tetramers are typically prepared with most of the commonly used fluorescent labels used for flow cytometry. One major advantage of the technique is that the label is already attached to the ...
H. Tagami et al., "Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis," Cell, 116:51-61, 2004. (Cited in 146 papers) Yoshihiro Nakatani's ...
A team of researchers at the University of California has found that the histone H3-H4 tetramer is a copper reductase enzyme. In their paper published in the journal Science, the group describes two ...
AstraZeneca and its partners at Ionis have been working on an antisense oligonucleotide therapy (eplontersen) to slow ...
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