Survivin, an important antiapoptotic protein, is expressed in tumors, whereas in normal tissues the expression of this protein is extremely low, defining a role for survivin as a cancer gene. Survivin ...
Much like ovarian cancer, pancreatic cancer has few symptoms. The majority of patients often aren't diagnosed until the disease is so advanced that treatment isn't likely to be effective. On top of ...
Adipose tissue (AT) has a central role in obesity-related metabolic imbalance through the dysregulated production of cytokines and adipokines. In addition to its known risk for cardiovascular disease ...
Cancer cells have many strategies for resisting therapy. One such strategy is survivin, a protein that drives the division of diseased cells and prevents them from dying. It is found in large ...
In a recent issue, Mesri et al. reported that the apoptosis inhibiting protein survivin can be inhibited in a wide variety of tumor cells using a dominant negative form of the protein. Survivin is ...
Role of Radiation Therapy in the Combined-Modality Treatment of Patients With Extensive Disease Small-Cell Lung Cancer: A Randomized Study PURPOSE: The survivin gene is a novel apoptosis inhibitor, ...
This project explores how survivin, a key protein in stiffness-dependent cellular processes, regulates vascular and cardiac cell behaviors linked to cardiovascular diseases. Arterial and cardiac ...
Immunohistopathologic studies were carried out on 26 tumor samples from a cohort of HR-NBL patients diagnosed at Children's Hospital of Philadelphia for the 2-year period from May 2003 to May 2005.
Non-small cell lung cancer (NSCLC) demonstrates a strong etiologic association with smoking. Although nicotine is not carcinogenic, it can induce cell proliferation and angiogenesis and suppress ...
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