Many drugs work by targeting proteins. Biologic medicines showed that proteins can be made into therapies too—in some cases using proteins from the body. Juvena Therapeutics works with a type of ...

Specially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the liver, according to a new study. The discovery improves the ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD), encompasses a spectrum of conditions ranging from simple steatosis to ...

Though Aβ tends to hog the research spotlight, scientists have steadily built a case for the importance of another APP fragment—secreted APP. Now, a paper in the January 11 Science explains how it ...

The first evidence that fat cells have a role beyond storing energy from excess food came from a strain of massively obese mutant mice. Before these mice, some researchers had suspected the cells were ...