Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in our cells. They now show that this complex also controls the processing of ...

LMU scientists show how bacteria control their protein biosynthesis through cell metabolism – possible approach for developing novel therapies. Protein biosynthesis – the process whereby cells produce ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Many of the “star proteins” of modern medicine—including signaling proteins, protein hormones, and the membrane receptors that make up roughly 60% of today’s drug targets—share an inconvenient trait: ...

A research team led by Professor Dr. Niels Gehring from the Institute for Genetics has shown that the coordinated interaction of three proteins plays a central role in nonsense-mediated mRNA decay ...

A forested hill and clouds are in the background of an image of a shallow pool of steaming water, with the ground underneath colored in shades of beige, red, and brown. Life may have first emerged in ...

Fruit ripening determines both food quality and postharvest losses worldwide, yet the molecular mechanisms controlling this ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

Tilting the scales at 4.7 megadaltons and reaching 1 micron in length, the newly discovered algal enzyme PKZILLA-1 is the largest protein ever identified in biology. Indeed, PKZILLA-1 is 25% larger ...