The drug’s effects on cardiovascular and inflammation markers outshined its failure to spur weight loss, analysts wrote.

Expert Rev Clin Pharmacol. 2010;3(3):321-329. Despite a propensity to block hERG channel function, as determined by electrophysiology, for a limited number of compounds no cardiac arrhythmias have ...

The majority of drug interactions today are attributed to the cytochrome P450 (CYP450) isoenzyme system. However, new data suggest that transport proteins also play a key role. One such transporter is ...

Semaglutide, the active ingredient in Wegovy and Ozempic, lowers major cardiac event risk, regardless of how much weight a ...

Researchers have developed a DNA-based therapy that targets the PCSK9 gene to lower cholesterol naturally. Using polypurine ...

A drug now prescribed for cardiovascular problems could become a new tool in physicians' arsenals to attack certain types of leukemia that so far have evaded effective treatments, researchers say. A ...

With more than 120 researchers representing more than 16 countries around the world, and disciplines ranging from biomedical engineering to medicinal chemistry to fluorescence-guided surgery, our ...