In an all-comer PROC population, across multiple dose cohorts, manageable safety profile of the combination was observed with low frequency of ...

A study of nearly 65,000 people suggests that devices coated with a drug called paclitaxel that are used for widening blocked arteries in legs and feet are safe and not linked to an increase in deaths ...

In this study, researchers aimed to investigate whether discontinuing premedications after 2 doses of paclitaxel is safe and feasible in some breast cancer patients.

Drug-eluting coronary-artery stents have been shown to decrease restenosis and therefore the likelihood that additional procedures will be required after percutaneous coronary intervention (PCI). We ...

The United States Food and Drug Administration today, in a letter to healthcare providers, reversed its restrictions on the use of paclitaxel-based therapies in peripheral vascular interventions (PVIs ...

Paclitaxel is a hydrophobic mitotic inhibitor with a powerful anti-cancer effect. It belongs to the group of taxanes (together with docetaxel), which are potent cytotoxic diterpenes derived from yew ...

SAN ANTONIO — In a first of its kind result, an investigational oral form of paclitaxel yielded a higher overall response rate than the IV form of the chemotherapy drug among women with metastatic ...

Protein-bound paclitaxel formulation is used to treat various types of cancer, including metastatic breast cancer and metastatic adenocarcinoma of the pancreas More than 168,000 people live with ...

In addition to inducing apoptosis, paclitaxel and analogs also regulate another programmed cell response known as autophagy. 5 Autophagy is characterized by the sequestration of cytoplasmic material ...

Patients with metastatic breast cancer who received an oral version of the chemotherapy drug experienced improved response rates and reductions in peripheral neuropathy compared to those who took the ...