Isaac Brown rushed for 130 yards and a touchdown before leaving late with a leg injury and Keyjuan Brown scored twice in the second half to lift No. 16 Louisville to a 28-16 victory over Virginia Tech.

Preview the Oct. 25 matchup between the Louisville Cardinals and Boston College Eagles with predictions, odds, over/under, spread, betting lines and more.

Isaac Brown ran for a career-high 205 yards and a touchdown to help No. 19 Louisville beat Boston College 38-24 on Saturday night.

As a reminder, in PFF's grading scale, 60.0 is the baseline for an "average" grade. 70.0-79.9 is considered above average, 80.0-89.9 is good, whereas 90.0 and higher is elite. On the opposite end of the spectrum, 59.9-50.0 is below average, 49.9-40.0 is considered poor, whereas 39.9 and below is very poor.

College football Week 9 odds, picks, predictions, TV channel, streaming for Boston College Eagles vs Louisville Cardinals ACC game Saturday, Oct. 25.

Louisville allowed Boston College to make this game much closer than it ever should have been. They started the fourth quarter with a clear opportunity to put the game away but it took until the two mintue warning to do so.

EA Sports released their first major ratings update for CFB26 since launch day, and several Cardinals had their overall rating impacted.

College football Week 10 odds, picks, predictions, TV channel, streaming for Louisville Cardinals vs Virginia Tech Hokies ACC game Saturday, Nov. 1.