A deeper look at what one supercentenarian’s labs can teach us about aging, cholesterol, and what really matters for ...

Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...

DDAH1 plays a critical role in hepatic lipid metabolism under fasting conditions by modulating FABP1 expression and AMPK/mTOR-mediated autophagy. The liver plays a central role in maintaining systemic ...

Mutations in the lipid transporter ABCA7 are known to elevate the risk of Alzheimer’s disease, but how they do so has been murky. Now, scientists led by Li-Huei Tsai at MIT in Cambridge, Massachusetts ...

AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...

A new mass spectrometry imaging system achieves 800 nm resolution. The technology enables single-cell analysis of lipid ...

The frequency of driver mutations in non-small cell lung cancer patients: The Turkish nation-wide, observational, Registurk-Lung study (updated analysis). Clinical analysis of AFFINITY trial: ...

Heart failure has increasingly been recognized as a complex, metabolism-driven syndrome that extends far beyond traditional models of hemodynamic ...

Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

Can a bitter Italian orange transform your lipids and blood sugar? The human data might surprise you. The mechanisms... even ...