Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This ...
How do neurons transport proteins? A new study reveals that Kinesin-2 motor subtypes regulate cargo specificity.
Precise intracellular transport is essential for neuronal function, yet the exact mechanism of selective cargo delivery by ...
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...
Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects ...
Kinesin-2 motor proteins transport cargo along neuronal microtubules to ensure proper cellular organization. This study shows that kinesin-2 exists as distinct assemblies with different compositions ...
The puzzle of memory has intrigued philosophers and intellects for a very long time. Plato and Aristotle believed that memory was found only in the realm of the soul and the mind, but there was ...