For decades, scientists have fought cancer by developing small molecules to inhibit kinase enzymes. These enzymes play an important role in a host of cellular processes, including phosphorylation and ...
Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...
December 18, 2025) Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center ...
The heat shock protein 90 kDa (Hsp90) chaperone machinery plays a crucial role in maintaining cellular homeostasis. Beyond its traditional role in protein folding, Hsp90 is integral to key pathways ...
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JMC Publication: Insilico’s AI platforms enable discovery of potent, selective, oral DGKα inhibitor to overcome checkpoint resistance
Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors view more . Credit: Insilico ...
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Scientists can finally answer an old question about cellular aging
Cells stop dividing when telomeres become too short to protect chromosomes, a process known as replicative senescence. But ...
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