A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

Explore the decades-long journey to map the full human genome, from early breakthroughs to the first complete, gapless DNA ...

The work demonstrates the power of ancient DNA to illuminate human biology and medicine in addition to history. A massive ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Today, genomics is saving countless lives and even entire species, thanks in large part to a commitment to collaborative and open science that the Human Genome Project helped promote. Twenty-five ...

A landmark study analyzing 22,000 genomes, including 10,000 ancient samples, has uncovered nearly 500 genetic changes driven ...

A pair of papers published this week in the two leading scientific journals mark the completion of the Human Genome Project and the start of a new project to find all of the functional elements in ...

Charles Gersbach and his colleagues are pursuing promising CRISPR technologies focused on controlling gene activity rather ...

In 2022, we reported the DNA sequences of 33 medieval people buried in a Jewish cemetery in Germany. Not long after we made ...

Scientists have decoded the world’s oldest human DNA sequence, beating the previous record by almost 300,000 years, and at the same time confusing what we know of our early relatives. Published in ...