Fatty acid isomers are responsible for an under-reported lipidome diversity across all kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary analysis by incomplete ...

Here we used single-particle analysis cryo-electron microscopy (cryo-EM) to determine structures of full-length human FASN (hFASN) with the cofactor NADPH in various conformational states, and with ...

Scientists at UC Irvine have found a way to potentially reverse age-related vision loss by targeting the ELOVL2 “aging gene” and restoring vital fatty acids in the retina. Their experiments in mice ...

Background Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with systemic inflammation and metabolic ...

The controversy surrounding omega-6 oils has created widespread confusion about their role in health and inflammation. While these essential fatty acids have been unfairly demonized, the real issue ...

The human heart is one of the hardest-working organs in the body. It never takes a day off and requires a continuous supply of energy to keep beating. To meet these enormous energy demands, heart ...