Dephosphorylation of NF-H has provided a useful quantitative molecular marker for the severity of EAE, emphasizing the association between axonal involvement and neurologic dysfunction and confirming ...

A new study has prompted scientists to reconsider a once-popular yet controversial idea in stroke research. Neuroscientists believed that, in the aftermath of a stroke, calming overexcited neurons ...

Excitotoxicity is the pathological process by which neurons are damaged and killed by the overactivations of receptors for the excitatory neurotransmitter glutamate, such as the NMDA receptor and AMPA ...

Reports of cognitive decline, symptom worsening and brain atrophy in bipolar disorder (BD) suggest that the disease progresses over time. The worsening neuropathology may involve excitotoxicity and ...

For decades, the duality of NMDA glutamate receptors has perplexed researchers. Essential players in synaptic activity, plasticity, and learning, these receptors can also trigger a toxic intraneuronal ...