A study shows that extra chromosomes in fetal cells create pre-leukemic clones that can persist for years, requiring later triggers to develop into leukemia, revealing a two-stage disease model.

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Researchers have revealed the mechanisms by which cells enter senescence because of an imbalance in the number of chromosomes. Chromosomal instability is a common trait in most solid tumors, such as ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from ...

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood ...

Like most bacteria, Vibrio cholerae lives under constant attack from viruses. To survive, bacteria equip themselves with ...

EPFL researchers show that cholera bacteria can exchange protective genes, including antiviral immune systems, when they live in aquatic environments. The finding helps explain how these pathogens ...