The basic structure of HFSC and components of its niche. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular ...

A recent review highlights the critical role of DNA exonucleases and endonucleases in immune response and disease management, shedding new light on their potential applications in genomic stability, ...

An innovative gene-editing strategy could establish a new way for the body to manufacture therapeutic proteins—including ...

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

The human immune system usually works wonders, protecting us from all sorts of diseases. However, if the immune system goes into overdrive, it can become even more dangerous than the diseases it ...

DMBT1 is a multifunctional secreted protein that plays a pivotal role in the body’s first line of defence across mucosal surfaces. Characterised by its scavenger receptor cysteine-rich (SRCR) domains, ...

Researchers have used a mouse model to show that infections in the intestine can change the composition of bile, a fluid that is generated in the liver and is crucial to digestion. Bile aids in the ...