Please provide your email address to receive an email when new articles are posted on . An increase in alpha-globin gene copy number was associated with a greater prevalence of chronic kidney disease ...

Thousands of children are born with AT every year, especially in South-East Asia, India, the Middle East, and the Mediterranean basin. When functioning normally, the genetic trait may provide ...

Feeling tired and weak all the time and having pale or yellowish skin may be connected to your genes. Alpha thalassemia is an inherited blood disorder in which specific gene mutations that get passed ...

Thalassemia is a common genetic condition affecting red blood cells. Children with severe forms of thalassemia often develop symptoms early in life, but effective treatment can manage the condition.

Whether you inherit alpha- or beta-thalassemia depends on which genes are affected. The number of affected genes can determine the subtype of alpha- or beta-thalassemia and the severity of your ...

A family of Albanian descent had an unusual form of beta thalassemia. The father of two children with mild thalassemia major had normal red-cell morphology and normal levels of hemoglobins A 2 and F, ...

Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the $^{\text{G}} ...

Thanks to groundbreaking in-utero blood transfusion technology, what was once a fatal diagnosis in the womb can now result in live births. However, this medical advancement created a new challenge: a ...

Base editing—the genome editing technique that alters base pairs using a nuclease-deficient Cas9 fused to a deaminase—was found to restart fetal hemoglobin expression in sickle cell disease (SCD) ...

Scientists at St. Jude Children’s Research Hospital and other colleagues say they have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of ...

For the first time in 43,000 years, a woolly mammoth has breathed again on earth. Well, not the mammoth itself but its hemoglobin, the stuff in red blood cells that takes on oxygen in the lungs and ...