GEN - Genetic Engineering and Biotechnology News

Gorilla Adenovirus Brings Natural Edge to Cancer Therapy

ReiThera’s gorilla-derived adenovirus platform combines innate tumor selectivity, low seroprevalence, and systemic-delivery advantages.
CNN

Little-known adeno-associated viruses may be key to unexplained hepatitis in kids, studies say

Scientists in the United Kingdom say they’ve found “strong circumstantial evidence” linking an obscure type of sidekick virus called adeno-associated virus to unexplained cases of liver damage in ...
Medical Xpress

Adeno-associated virus vectors can trigger innate immune pathways

Adeno-associated virus (AAV)-based viral vectors used in human gene therapy can trigger innate immune pathways, leading to the initiation of adaptive immune responses. A new review article published ...
C&EN

Gene therapy companies look beyond adeno-associated viruses

Gene therapy has largely relied on adeno-associated viruses (AAVs) as vessels to carry and deliver new genes to replace defective or missing ones in people with gene-related conditions. AAVs are small ...
Medical Xpress

Enabling adeno-associated virus gene therapy despite preexisting humoral immunity

The use of a monoclonal antibody that reduced circulating IgG levels, led to a decrease in preexisting neutralizing antibodies (NAbs) to adeno-associated virus (AAV). The study, which showed that this ...
CNN

Little-known adeno-associated viruses may be key to unexplained hepatitis in kids, studies say

Adeno-associated virus 2 was present in high amounts in liver tissue and blood in nearly all the children with unexplained hepatitis in the studies. And it was only rarely found in healthy kids, those ...
WESH

Little-known adeno-associated viruses may be key to unexplained hepatitis in kids, studies say

Video above: Boston doctor describes severity of pediatric hepatitis casesScientists in the United Kingdom say they've found "strong circumstantial evidence" linking an obscure type of sidekick virus ...